1. Identification of Novel Small Molecule Activators of Nuclear Factor-kappa B With Neuroprotective Action Via High-Throughput Screening Author(s): Manuvakhova MS, Johnson GG, White MC, et al. Source: JOURNAL OF NEUROSCIENCE RESEARCH Volume: 89 Issue: 1 Pages: 58-72 Published: JAN 2011
  2. Grimaldi M Astrocytes refill intracellular Ca2+ stores in the absence of cytoplasmic [Ca2+] elevation: A functional rather than a structural ability. JOURNAL OF NEUROSCIENCE RESEARCH 84 (8): 1738-1749 DEC 2006
  3. Wilson SJ, Roche AM, Kostetskaia E, et al. Dimerization of the human receptors for prostacyclin and thromboxane facilitates thromboxane receptor-mediated cAMP generation J BIOL CHEM 279 (51): 53036-53047 DEC 17 2004
  4. Watson WD, Facchina SL, Grimaldi M, et al. Sarco-endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitors identify a novel calcium pool in the central nervous system J NEUROCHEM 87 (1): 30-43 OCT 2003
  5. Grimaldi M, Maratos M, Verma A Transient receptor potential channel activation causes a novel form of [Ca2+](i) oscillations and is not involved in capacitative Ca2+ entry in glial cells J NEUROSCI 23 (11): 4737-4745 JUN 1 2003
  6. Fiebich BL, Schleicher S, Spleiss O, et al.Mechanisms of prostaglandin E2-induced interleukin-6 release in astrocytes: possible involvement of EP4-like receptors, p38 mitogen-activated protein kinase and protein kinase C
    J NEUROCHEM 79: (5) 950-958 DEC 2001
  7. Grimaldi M, Atzori M, Ray P, et al.Mobilization of calcium from intracellular stores, potentiation of neurotransmitter-induced calcium transients, and capacitative calcium entry by 4-aminopyridineJ NEUROSCI 21: (9) 3135-3143 MAY 1 2001
  8. Van Wagoner NJ, Choi CH, Repovic P, et al. Oncostatin M regulation of interleukin-6 expression in astrocytes: Biphasic regulation involving the mitogen-activated protein kinases ERK1/2 and p38 J NEUROCHEM 75: (2) 563-575 AUG 2000
  9. Fleisher LN, McGahan MC, Ferrell JB Rabbit pigmented ciliary epithelium produces interleukin-6 in response to inflammatory cytokines EXP EYE RES 70: (3) 271-279 MAR 2000
  10. Van Wagoner NJ, Benveniste EN   Interleukin-6 expression and regulation in astrocytes   J NEUROIMMUNOL 100: (1-2) 124-139 DEC 1999
  11. Grimaldi M, Favit A, Alkon DL cAMP-induced cytoskeleton rearrangement increases calcium transients through the enhancement of capacitative calcium entry J BIOL CHEM 274: (47) 33557-33564 NOV 19 1999 
  12. Arcone R, Pagliuca MG, Chinali A, Grimaldi M, Schettini G, Gast A, Pietropaolo C Thrombin mutants with altered enzymatic activity have an impaired mitogenic effect on mouse fibroblasts and are inefficient modulators of stellation of ratcortical astrocytes BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1451: (1) 173-186 AUG 12 1999
  13. Brenneman DE, Hauser J, Spong CY, Phillips TM, Pert CB, Ruff M VIP and D-ala-peptide T-amide release chemokines which prevent HIV-1 GP120-induced neuronal death BRAIN RESEARCH 838: (1-2) 27-36 AUG 14 1999
  14. Grimaldi M, Cavallaro S Functional and molecular diversity of PACAP/VIP receptors in cortical neurons and type I astrocytes EUR J NEUROSCI 11: (8) 2767-2772 AUG 1999
  15. Janabi N, Hau I, Tardieu M Negative feedback between prostaglandin and alpha- and beta-chemokine synthesis in human microglial cells and astrocytes J. IMMUNOL 162: (3) 1701-1706 FEB 1 1999 
  16. Munoz-Fernandez MA, Fresno M The role of tumour necrosis factor, interleukin 6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system PROG NEUROBIOL 56: (3) 307-340 OCT 1998 
  17. Hampson AJ, Grimaldi M, Axelrod J, et al. Cannabidiol and (-)Delta(9)-tetrahydrocannabinol are neuroprotective antioxidants P NATL ACAD SCI USA 95: (14) 8268-8273 JUL 7 1998 
  18. Tang YM, Feng Y, Wang X Calcitonin gene-related peptide potentiates LPS-induced IL-6 release from mouse peritoneal macrophages J NEUROIMMUNOL 84: (2) 207-212 APR 15 1998 
  19. Zanassi P, Paolillo M, Schinelli S Coexpression of phospholipase A(2) isoforms in rat striatal astrocytes NEUROSCI LETT 247: (2-3) 83-86 MAY 15 1998 
  20. Gruol DL, Nelson TE Physiological and pathological roles of interleukin-6 in the central nervous system MOL NEUROBIOL 15: (3) 307-339 DEC 1997 
  21. Minghetti L, Levi G Microglia as effector cells in brain damage and repair: Focus on prostanoids and nitric oxide PROG NEUROBIOL 54: (1) 99-125 JAN 1998 
  22. Passalacqua M, Patrone M, Picotti GB, et al. Stimulated astrocytes release high-mobility group 1 protein, an inducer of LAN-5 neuroblastoma cell differentiation NEUROSCIENCE 82: (4) 1021-1028 FEB 1998 
  23. Ballestas ME, Benveniste EN Elevation of cyclic AMP levels in astrocytes antagonizes cytokine-induced adhesion molecule expression J NEUROCHEM 69: (4) 1438-1448 OCT 1997 
  24. Gadient RA, Otten UH Interleukin-6 (IL-6) - A molecule with both beneficial and destructive potentials PROG NEUROBIOL 52: (5) 379-390 AUG 1997 
  25. Patrizio M, Slepko N, Levi G Opposite regulation of adenylyl cyclase by protein kinase C in astrocyte and microglia cultures J NEUROCHEM 69: (3) 1267-1277 SEP 1997 
  26. Grimaldi M, Florio T, Schettini G Somatostatin inhibits interleukin 6 release from rat cortical type I astrocytes via the inhibition of adenylyl cyclase BIOCHEM BIOPH RES CO 235: (1) 242-248 JUN 9 1997 
  27. Kiriyama Y, Murayama T, Tokumitsu Y, et al. Protein kinase A-dependent IL-6 production induced by calcitonin in human glioblastoma A172 cells J NEUROIMMUNOL 76: (1-2) 139-144 JUN 1997 
  28. Straub RH, Herrmann M, Berkmiller G, et al. Neuronal regulation of interleukin 6 secretion in murine spleen: Adrenergic and opioidergic control J NEUROCHEM 68: (4) 1633-1639 APR 1997 
  29. Florio T, Grimaldi M, Scorziello A, et al. Intracellular calcium rise through L-type calcium channels, as molecular mechanism for prion protein fragment 106-126-induced astroglial proliferation BIOCHEM BIOPH RES CO 228: (2) 397-405 NOV 12 1996 
  30. Ganea D Regulatory effects of vasoactive intestinal peptide on cytokine production in central and peripheral lymphoid organs ADV NEUROIMMUNOL 6: (1) 61-74 1996 
  31. Patrizio M, Riitano D, Costa T, et al. Selective enhancement by serum factors of cyclic AMP accumulation in rat microglial cultures NEUROCHEM INT 29: (1) 89-96 JUL 1996 
  32. Fiebich BL, Biber K, Gyufko K, et al. Adenosine A(2b) receptors mediate an increase in interleukin (IL)-6 mRNA and IL-6 protein synthesis in human astroglioma cells J NEUROCHEM 66: (4) 1426-1431 APR 1996 
  33. Benveniste EN, Huneycutt BS, Shrikant P, et al. Second messenger systems in the regulation of cytokines and adhesion molecules in the central nervous system BRAIN BEHAV IMMUN 9: (4) 304-314 DEC 1995 
  34. Huneycutt BS, Benveniste EN Regulation of astrocyte cell biology by the cAMP/protein kinase A signaling pathway ADV NEUROIMMUNOL 5: (3) 261-269 1995 
  35. GRIMALDI M, ARCONE R, CILIBERTO G, et al. SYNERGISTIC STIMULATION OF INTERLEUKIN-6 RELEASE AND GENE-EXPRESSION BY PHORBOL ESTERS AND INTERLEUKIN-1-BETA IN RAT CORTICAL ASTROCYTES - ROLE OF PROTEIN-KINASE-C ACTIVATION AND BLOCKADE J NEUROCHEM 64: (5) 1945-1953 MAY 1995 
  36. Grimaldi M, Navarra P, Pozzoli G, Preziosi P, Schettini G. Bacterial lipopolysaccharide increases interleukin-6 and prostaglandin release in rat cortical type Iastrocytes by different mechanisms: Role of anti-inflammatory agents BIOCHEM BIOPH RES CO 250: (3) 798-804 SEP 29 1998