Total impact factor 233;  mean impact factor 4.5; total number of citations 1387 (246); mean citations per publication 26 (for
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  1. Johnson G.G., White M., and Grimaldi M., Stressed to death:  Targeting Endoplasmic Reticulum Stress Response Induced Apoptosis in Gliomas.
    Current Pharmaceutical Design 17(3):284-292 (2011). I.F.=4.4. # of citations=1
  2. Johnson G.J., Manuvakhova M.S., , White M.C., Ananthan S., Sosa M., Maddox C, McKellip S., Rasmussen L, Wennerberg K, Hobrath J.V., White L.E.,
    Maddry J.A. and Grimaldi M. Identification of Novel Small Molecules Activators of NF-kB with Neuroprotective Action via High Throughput Screening.
    Journal of Neuroscience 89(1)-58-72 Research (2011). Volume 89(1):58–72. I.F.=3.6. # of citations=0
  3. Mustafa T., Welsh J., Grimaldi M., Eiden L.  PAC1 hop receptor activation facilitates catecholamine secretion selectively through 2-APB-sensitive Ca2+
    channels in PC12 cells. Cellular Signalling.  22(10)1420-1426 (2010). I.F.=4.2. # of citations=1  
  4. Mustafa T., Grimaldi M, Eiden L. The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for PACAP-evoked
    neurosecretion. The Journal of Biological Chemistry 282(11) 8079-8091 (2007).  I.F. 5.5. # of citations=12
  5. Grimaldi M. Astrocytes refill intracellular Ca2+ stores in the absence of cytoplasmic [Ca2+] elevation: a functional rather than a structural ability. J.
    Neuroscience Research 88(8):1738-49 (2006).I.F.=3.1  # of citations=3  see the Journal cover page
  6. A. Pascale, D..L. Alkon, and M. Grimaldi.  Translocation of Protein Kinase C-ßII in astrocytes requires organized actin cytoskeleton and is not
    accompanied by synchronous RACK1 relocation. Glia 46(2):169-182 (2004). I.F. 5.6. # of citations=10  see the Journal cover image
  7. Zhao W., Weissman D.M. and Grimaldi M., Specific Localization of the annexin II heterotetramer in brain lipid raft fractions and its changes in spatial
    learning J. Neurochemistry 90(3):609-620 (2004).  I.F.=4.7.  # of citations=19
  8. Grimaldi M., Maratos M., Verma A. Transient receptor potential channel Activation Causes a novel Form of [Ca2+]i Oscillations and is not involved in
    Capacitative Ca2+ entry in Glial Cells. J. Neuroscience 23(11):4737-4745 (2003) I.F. 7.4. # of citations=41
  9. Watson W., Facchina S., Grimaldi M., Verma A. SERCA inhibitors identify a novel calcium pool in the central  nervous system. J. Neurochemistry  87:30-
    43 (2003). I.F. 4.7. # of citations=13
  10. Hampson A.J. and Grimaldi M. Glutamate toxicity studies unmask a putative 12-HETE receptor in cortical neurons. J. Neuroscience 22(1):257-264
    (2002). I.F. 7.4. # of citations=22
  11. Haak L.L., Grimaldi M., Smaili S.S., Russell J.T.  Mitochondria Regulate Ca2+ Wave Initiation and Inositol Trisphosphate Signal Transduction in
    Oligodendrocyte Progenitors. J. Neurochemistry 80(3):405-415 (2002). I.F.=4.7. # of citations=18
  12. Hamelink C., Hyeon-Woo L., Yun C., Grimaldi M., Eiden L.E. Coincident elevation of cyclic AMP and calcium influx by PACAP 27 synergistically
    regulates VIP gene transcription through a novel PKA-independent signaling pathway. J. Neuroscience 22(13):5310-5320 (2002). I.F. 7.4. # of
    citations=35
  13. Grimaldi M., Atzori M., Ray P. Alkon D.L. Mobilization of calcium from intracellular stores, potentiation of neurotransmitter induced calcium transients and
    capacitative calcium entry by 4-aminopyridine. J. Neuroscience 21(9):3135-3143 (2001). I.F.=7.5. # of citations=26
  14. Hampson A.J. and Grimaldi, M. Cannabinoid receptor activation and elevated cyclic AMP reduce glutamate neurotoxicity.  European J. of Neuroscience
    13(8):1529-1536 (2001). I.F.=3.3. # of citations=39
  15. Hampson A.J., Grimaldi M., Axlerod J., Wink D. Neuroprotective antioxidants from marijuana. In Reactive oxygen species: from radiation to molecular
    biology and its implications. A Festschrift to the work of Daniel Gilbert. Annals of New York Academy of Sciences 899:274-282 (2000) I.F.=2.3. # of
    citations=87
  16. Grimaldi M., Favit A., Alkon.D.L. Prevention of b-amyloid neurotoxicity by blockade of the ubiquitin-proteasome proteolytic pathway. J. Neurochemistry
    75(3):1258-1263 (2000) I.F.=4.7. # of citations=25
  17. D’agata V., Grimaldi M., Pascale A., Cavallaro S. Regional and cellular expression of Parkin in the rat  cerebral cortex. European Journal of
    Neuroscience 12:3583-3588 (2000) I.F.=3.4. # of citations=16
  18. Haak L.L. , Grimaldi M., Russell J.T. Mithocondria in myelinating cells: calcium signaling in olygodendrocyte precursor cells. Cell Calcium 28(5/6):297-
    306 (2000) I.F.=4.5. # of citations=12
  19. Grimaldi M., Cavallaro S. Expression and coupling of PACAP/VIP receptors in cortical neurons and type I astrocytes. Annals of New York Academy of
    Sciences 921:312-316 (2000) I.F.=2.3. # of citations=5
  20. Grimaldi M., Cavallaro S. Functional and molecular diversity of PACAP/VIP receptors in cortical neurons and type I astrocytes. European Journal of
    Neuroscience 11(8):2767-2772 (1999) I.F.=3.4; # of citations=45
  21. Arcone R., Pagliuca M.G., Chinali A., Grimaldi M. Gast A., Pietropaolo C. Thrombin mutants with altered enzymatic activity have an impaired mitogenic
    effect on NIH3T3 cells and are inefficient modulators of stellation of rat cortical astrocytes. Biochimica et Biophysica Acta 1451 (1):173-186 (1999) I.F.=4.
    6; # of citations=5
  22. Grimaldi M., Favit A., Alkon D.L. cAMP-induced cytoskeleton rearrangement increases calcium transients through the enhancement of capacitative
    calcium entry. The Journal of Biological Chemistry Vol. 274(47):33557-33564 (1999). I.F.=5.5; # of citations=43
  23. Favit A, Grimaldi M., Nelson T.J., Alkon D.L. Alzheimer's-specific effects of soluble ß-amyloid on PKCa and PKCg degradation in human fibroblasts.
    Proceedings of the National Academy of Science USA 95(10):5562-5567 (1998) I.F.=9.4; # of citations=55
  24. Hampson A.J., Grimaldi M., Axelrod J., Wink D. Cannabidiol and (-)-/delta9 -tethra-hydrocannabidiol are neuroprotective antioxidants. Proceedings of
    the National Acadademy of Science USA   95(14):8268-8273 (1998) I.F.=9.4; # of citations=303 Press Releases (articoli di giornale che citano il lavoro)
  25. Grimaldi M., Navarra P., Pozzoli G., Preziosi P. Bacterial lipopolysaccharide increases interleukin-6 and prostaglandin release in rat cortical type I
    astrocytes by different mechanisms: role of anti-inflammatory agents. Biochememical and Biophysical Research Communications Vol. 250(3):798-804
    (1998) I.F.=2.2; # of citations=12
  26. Grimaldi M., Arcone R., Ciliberto G. Synergistic stimulation of IL-6 release and gene expression by phorbol esters and IL-1b in rat cortical astrocytes:
    role of protein kinase C blockade and activation. Journal of Neurochemistry 64:1945-1953 (1995) I.F.=4.7; # of citations=16
  27. Ventra C., Meucci O., Grimaldi M., Scorziello A., Porcellini A. Absence of D2s dopamine receptor in the prolactin-secreting MMQ pituitary clone:
    characterization of a wild D2l receptor coupled to native transduction mechanism. Journal of Molecular Endocrinology 14(3):375-389 (1995) I.F.=3.2; # of
    citations=4
  28. Grimaldi M., Florio T. Somatostatin inhibits interleukin 6 release from rat cortical type I astrocytes, via the inhibition of adenylyl cyclase. Biochememical
    And Biophysical Research. Communications 235(1):242-248 (1997) I.F.=2.2; # of citations=20
  29. Florio T., Grimaldi M., Scorziello A., Salmona M., Bugiani M., Tagliavini F., Forloni G. Intracellular calcium rise through L-type calcium channels, as a
    molecular mechanism for prion protein fragment 106-126-induced astoglial proliferation. Biochememical and Biophysical Research Communications 228
    (2):397-405 (1996) I.F.=2.2; # of citations=52
  30. Ventra C., Grimaldi M., Meucci O., Scorziello A., Apicella A., Filetti E., Marino A. Aniracetam improves behavioural responses and facilitates signal
    transduction in the rat brain. Journal of Psycopharmacology 8(2):109-117 (1994) I.F.=4; # of citations=2
  31. Meucci O., Scorziello A., Avallone A., Ventra C., Grimaldi M., Berlingieri M.T. Alpha 1A and alpha 1B-adrenergic receptors mediate the effect of
    norepinephrine on cytosolic calcium levels in rat PC CL3 thyroid cells. Thyrotropin modulation of alpha 1B-linked response via a cAMP/protein kinase A-
    dependent pathway. Endocrinology 134(1):424-431 (1994) I.F.=4.9; # of citations=16
  32. Pozzoli G., Costa A., Grimaldi M., Preziosi P., Grossman A., Navarra P.L. Lypopolysaccaride modulation of eicosanoids and corticotrophin releasing
    hormone relase from rat hypothalamic explants and astrocyte cultures in vitro: evidence for the involvementof prostaglandin E2 but not F2a, and lack of
    effect of nerve growth factor. Journal of Endocrinology 140:103-109 (1994) I.F.=2.8; # of citations=26
  33. Grimaldi M., Pozzoli G., Navarra P., Preziosi P. Vasoactive Intestinal peptide and forskolin stumulate interleukin 6 production by rat cortical astrocytes in
    culture via a cAMP-dependent prostaglandins-independent mechanism. Journal of Neurochemistry 63:344-350 (1994) I.F.=4.7; # of citations=37
  34. Grimaldi M., Navarra P., Pozzoli G., Preziosi P. Regulation of IL-6 production by cAMP-protein kinase A-pathway in rat astrocytes. Pharmacological
    Research 30(1):13-24 (1994) I.F.=3.3; # of citations=9
  35. Meucci O., Berlingieri M.T., Fusco A., Scorziello A., Santoro M., Grieco M., Grimaldi M. Norepinephrine and Thyrotropin stimulation of [Ca++]i in PC Cl3
    rat thyroid epitelial cell line: effect of transformation by E1A gene of adenovirus and polyomavirus middle-T antigen gene. Life Sciences 52:891-899
    (1993) I.F.=2.5; # of citations=6
  36. Florio T., Meucci O., Grimaldi M., Ventra C., Cocozza E., Avallone A., Postiglione A., Marino A. Acetyl-L-Carnitine treatment Effect of on brain adenylate
    cyclase activity in young and aged rats. European Neuropsychopharmacology 3:95-101 (1993) I.F.=3.6; # of citations=1
  37. Scorziello A., Landolfi E., Grimaldi M., Meucci O., Ventra C., Avallone A., Postiglione A. Direct effect of Adenosine on Prolactin secretion at the level of
    the single rat lactotroph: involvement of pertussin toxin-sensitive and -insensitive transducing mechanism. Journal of Molecular Endocrinology 11:325-
    334 (1993) I.F.=3.2; # of citations=11
  38. Meucci O., Berlingieri M.T., Fusco A., Scorziello A., Santoro M., Grieco M., Grimaldi M. Norepinephrine and Thyrotropin stimulation of [Ca++]i in PC Cl3
    rat thyroid epitelial cell line: effect of transformation by E1A gene of adenovirus and polyomavirus middle-T antigen gene. Life Sciences 52:891-899
    (1993) I.F.=2.5; # of citations=6
  39. Florio T., Meucci O., Grimaldi M., Ventra C., Cocozza E., Avallone A., Postiglione A., Marino A. Acetyl-L-Carnitine treatment Effect of on brain adenylate
    cyclase activity in young and aged rats. European Neuropsychopharmacology 3:95-101 (1993) I.F.=3.6; # of citations=1
  40. Scorziello A., Landolfi E., Grimaldi M., Meucci O., Ventra C., Avallone A., Postiglione A. Direct effect of Adenosine on Prolactin secretion at the level of
    the single rat lactotroph: involvement of pertussin toxin-sensitive and -insensitive transducing mechanism. Journal of Molecular Endocrinology 11:325-
    334 (1993) I.F.=3.2; # of citations=11
  41. Meucci O., Grimaldi M., Scorziello A., Govoni S., Bergamaschi S., Yasumoto T.  Maitotoxin-induced intracellular calcium rise in PC12: involvement of
    dihydropiridine-sensitive and omega-conotoxin-sensitive calcium channels and phosphoinositides breakdown. Journal of Neurochemistry 59(2):679-688
    (1992) I.F.=4.5; # of citations=25
  42. Ventra C., Florio T., Meucci O., Grimaldi M., Scorziello A., Talia S., Postiglione A. Molecular mechanisms mediating the effects of L-alpha-
    glycerylphosphorylcholine, a new cognition enhancing drug, on behavioral and biochemical parameters in young and aged rats. Pharmacology
    Biochemistry and Behavior 43:139-151 (1992) I.F.=2.7; # of citations=8
  43. Grimaldi M., Meucci O., Scorziello A., Florio T., Ventra C., De Mercato R. Interleukin 6 modulation of second messengers systems in anterior pituitary
    cells. Life Sciences 51:1243-48 (1992) I.F.=2.5; # of citations=9
  44. Meucci O., Landolfi E., Scorziello A., Grimaldi M., Ventra C., Florio T., Avallone A. Dopamine and Somatostatin inhibition of Prolactin secretion from
    MMQ pituitary cells: role of adenosine triphosphate-sensitive potassium channels. Endocrinology 131:1942-1947 (1992) I.F.=4.9; # of citations=14
  45. Ventra C., Florio T., Grimaldi M., Meucci O., Marino A. Modulation by GTP of basal and agonist-stimulated striatal adenylate cyclase activity following
    chronic blockade of D-1 and D-2 dopamine receptors: involvement of G-proteins in the development of dopamine receptor supersensitivity. Journal of
    Neurochemistry 59(5):1667-1674 (1992) I.F.=4.5; # of citations=17
  46. Santangelo F., Grimaldi M., Landolfi E., Ventra C., Belfiore A., Meucci O., Santillo M., Mondola P. Effect of calf thymus protein on prolactin release and
    second messenger systems in rat pituitary cells. Progress in NeuroEndocrinoImmunology 5(3):172-178 (1992) I.F.=1.429
  47. Meucci O., Grimaldi M., Florio T., Landolfi E., Scorziello A., Ventra C., Dihydropyridine modulation of K+-activated calcium channels in PC12 cells: effect
    of pertussis toxin pretreatment. Journal of Neurochemistry 56:805-811 (1991) I.F.=4.5; # of citations=11
  48. Grimaldi M., Landolfi E., Meucci O., Ventra C., Florio T., Scorziello A., Marino A., Role of Interleukin-6 in the neuroendocrine system. Acta Neurologica
    13:361-367 (1991) # of citations=8
  49. Marino A., Florio T., Meucci O., Landolfi E., Grimaldi M., Ventra C. Fipexide improvement of cognitive functions in rat: behavioral and neurochemical
    studies. Pharmacological Research 22(Suppl.2):179-187 (1990) I.F.=3.3; # of citations=6
  50. Landolfi E., Meucci O., Florio T., Grimaldi M., Ventra C., Marino A. Adenosine and its analogue N6- phenylisopropyladenosine (PIA) modulate anterior
    pituitary adenylate cyclase activity and prolactin secretion. Journal of Molecular Endocrinology 5:69-76 (1990) I.F.=3.2; # of citations=14
  51. Florio T., Meucci O., Landolfi E., Grimaldi M.,Ventra C., Marino A. Interleukin 1 modulation of anterior pituitary function: effects on prolactin release and
    post-receptor transducing mechanisms. Annals of The New York Academy of Sciences 594: 489-491 (1990) I.F. = 2.3; # citations=4
  52. Florio T., Meucci O., Landolfi E., Grimaldi M., Scala G., Leong D.A., Marino A. Interleukin 1b modulation of prolactin secretion from rat anterior pituitary
    cells: involvement of adenylate cyclase activity and calcium mobilization. Endocrinology 126:1435-1441 (1990) I.F.=4.9; # of citations=35
  53. Florio T., Meucci O., Landolfi E., Grimaldi M., Ventra C., Marino A. Somatostatin inhibition of adenylate cyclase activity in different brain areas. Brain
    Research 492:65-71 (1989) I.F.=2.5; # of citations=68
  54. Landolfi E., Grimaldi M., Meucci O., Postiglione A., Florio T., Ventra C. Interleukin 1b inhibition of TRH-stimulated prolactin secretion and
    phoshoinositide turnover. Biochemical And Biophysical Research Communications Vol. 165(1):496-505 (1989) I.F.=2.7; # of citations=8
  55. Florio T., Magri G., Grimaldi M., Meucci O., Landolfi E., Marino A. Somatostatin and SMS 201-995 reversal of the impairment of cognitive functions
    induced by cysteamine depletion of brain somatostatin.  European Journal of Pharmacology 151: 399-407 (1988) I.F.=2.8; # of citations=49
  56. Meucci O., Florio T., Grimaldi M., Landolfi E., Magri G., Yasumoto T. Pertussis Toxin pretreatment abolishes dihydropyridine inhibition of calcium flux in
    the 235-1 pituitary cell line. Biochemical And Biophysical Research Communications Vol. 151(1):361-369 (1988) I.F.=2.7; # of citations=9
  57. Florio T., Meucci O., Scala G., Landolfi E., Grimaldi M. Effect of IL-1ß on transducing mechanisms in 235-1 clonal pituitary cells. Part 1: modulation of
    adenylate cyclase activity. Biochemical And Biophysical Research Communications 155: 1089-1096 (1988) I.F.=2.7; # of citations=15
  58. Meucci O., Florio T., Scala G., Landolfi E., Grimaldi M. Effect of IL-1ß on transducing mechanisms in 235-1 clonal pituitary cells. Part II: modulation of
    calcium fluxes. Biochemical And Biophysical Research Communications 155: 1097-1104 (1988) I.F.=2.7; # of citations=15       
  59. Meucci, O; Florio, T; Grimaldi, M; Landolfi, E; Magri, G. Role of G-proteins in mediating dihydropyridine receptor coupling with voltage sensitive calcium
    channels. Pharmacological research communications. I.F.=1.2; 20(12): 1083-4 (1988) # of citations=4  
  60. Florio, T., Magri, G., Landolfi, E., Meucci, O., Grimaldi, M., Marino, A. Depletion of brain somatostatin (SRIF) by cysteamine (CSH) induces impairment
    of cognitive functions in rat: Reversal by administration of exogenous SRIF or its analogue SMS 201-995. Pharmacological Research Communications 20
    (3):241-242   (1988). # of citations 3